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Exosomes and Tumor Suppressor Gene Pathways

Here are several studies to review:


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Read about studies that show the amazing possibilities of Exosomes for medical treatments:

The regulation of exosome secretion: a novel function of the p53 protein.


β-Elemene against human lung cancer via up-regulation of P53 protein expression to promote the release of exosome.


Different gDNA content in the subpopulations of prostate cancer extracellular vesicles: apoptotic bodies, microvesicles, and exosomes.


Silencing of human papillomavirus (HPV) E6/E7 oncogene expression affects both the contents and the amounts of extracellular microvesicles released from HPV-positive cancer cells.


Nuclear pore component Nup98 is a potential tumor suppressor and regulates posttranscriptional expression of select p53 target genes.


Analysis of exosome release and its prognostic value in human colorectal cancer.


Effect of 5-aza-2'-deoxycytidine on immune-associated proteins in exosomes from hepatoma.


The regulation of the endosomal compartment by p53 the tumor suppressor gene.

https://www.ncbi.nlm.nih.gov/pubmed/19302216


Exosome secretion, including the DNA damage-induced p53-dependent secretory pathway, is severely compromised in TSAP6/Steap3-null mice.

 
 
 

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